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Accessory protein 3b

Annotation score:1 out of 5

The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score cannot be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.

– Protein predicted i

This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.

Select a section on the left to see content.

This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.

Names & Taxonomy i

This subsection of the Names and taxonomy section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.

Information which has been generated by the UniProtKB automatic annotation system, without manual validation.

Automatic assertion according to rules i

Automatic assertion according to rules i

This subsection of the Names and taxonomy section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.

Information which has been imported from another database using automatic procedures.

Automatic assertion inferred from database entries i

This subsection of the Names and taxonomy section provides information on the name(s) of the organism that is the source of the protein sequence.

Automatic assertion inferred from database entries i

This subsection of the Names and taxonomy section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.

This subsection of the Names and taxonomy section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.

This subsection of the Names and taxonomy section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.

This subsection of the Names and taxonomy section is present for entries that are part of a proteome, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.

A UniProt proteome can consist of several components.
The component name refers to the genomic component encoding a set of proteins.

This section provides information on the tertiary and secondary structure of a protein.

3D structure databases

SWISS-MODEL Repository – a database of annotated 3D protein structure models

Database of comparative protein structure models

This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.

Family & Domains i

Family and domain databases

Integrated resource of protein families, domains and functional sites

Pfam protein domain database

This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight. The information is filed in different subsections. The current subsections and their content are listed below:

This subsection of the Sequence section indicates if the canonical sequence displayed by default in the entry is complete or not.

Sequence status i : Complete.

The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.

It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.

However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).

The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x 64 + x 4 + x 3 + x + 1. The algorithm is described in the ISO 3309 standard.

Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.
Cyclic redundancy and other checksums
Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993))

Checksum: i 421D023897267F42

Sequence databases

EMBL nucleotide sequence database

GenBank nucleotide sequence database

DNA Data Bank of Japan; a nucleotide sequence database

This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (UniRef).

Similar proteins i

  • 100% Identity
  • 90% Identity
  • 50% Identity

This section is used to point to information related to entries and found in data collections other than UniProtKB.

Sequence databases
3D structure databases
SMR i Q778S4
ModBase i Search.
Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

MobiDB: a database of protein disorder and mobility annotations

This section provides general information on the entry.

Entry information i

This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.

This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.

This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the canonical sequence are also displayed.

This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (reviewed) or to the computer-annotated TrEMBL section (unreviewed).

Accessory protein 3b Annotation score:1 out of 5 The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score cannot be used as a